How Does Liver Dysfunction Affect the Sinusoids and Bile Ducts?
Liver dysfunction can severely impact the sinusoids and bile ducts. In conditions like cirrhosis, the sinusoids become constricted by fibrous tissue, impairing blood flow. This can lead to portal hypertension. The bile ducts may also be affected, showing signs of cholestasis, where bile accumulates within the liver due to impaired bile flow, or biliary proliferation in response to injury.
