1. Proliferation: Basal cells divide and move upward. 2. Differentiation: As cells migrate through the layers, they begin to produce keratin and other proteins. 3. Keratin Accumulation: In the granular layer, cells accumulate keratohyalin granules. 4. Cell Death: Cells in the cornified layer lose their nuclei and organelles, becoming flattened and fully keratinized.
