How Does Haploinsufficiency Affect Cellular Function?
Cells rely on the balanced expression of genes to maintain homeostasis. When one copy of a gene is non-functional, the cell's ability to produce sufficient amounts of a protein or enzyme is compromised. This can lead to dysregulation in various cellular processes such as signal transduction, cell cycle regulation, and metabolic pathways. Consequently, the affected tissues may exhibit abnormal growth, differentiation, or function.
