What are the Therapeutic Implications of Targeting eIF2α?
Given its central role in stress response and disease, targeting eIF2α presents a promising therapeutic strategy. For example, small molecules that inhibit eIF2α kinases or modulators that prevent its phosphorylation are under investigation for treating neurodegenerative diseases and certain cancers. Understanding the histological context of eIF2α function can guide the development of these targeted therapies.
