How Does Escherichia coli Interact with Host Tissues?
E. coli interacts with host tissues through various mechanisms. Pathogenic strains of E. coli can adhere to the mucosal lining of the gastrointestinal tract using fimbriae and pili. This attachment is crucial for colonization and subsequent infection. Some strains produce toxins, such as Shiga toxin, which can disrupt cellular function and lead to tissue damage.