How do the Islets of Langerhans Change in Disease?
In diseases such as diabetes, the islets undergo significant changes:
Type 1 Diabetes: Characterized by autoimmune destruction of beta cells, leading to insulin deficiency. Type 2 Diabetes: Involves insulin resistance and often beta cell dysfunction, resulting in impaired insulin secretion. Pancreatic Cancer: Tumors can disrupt the normal architecture and function of the islets, leading to endocrine insufficiency.
