SOD mimetics function by catalyzing the conversion of the superoxide anion (O2â¢-) into less harmful molecules like oxygen (O2) and hydrogen peroxide (H2O2). This activity is crucial in preventing the accumulation of reactive oxygen species (ROS), which can cause cellular damage, apoptosis, and necrosis. By mitigating oxidative stress, SOD mimetics help maintain cellular homeostasis and protect tissues from damage.