Preganglionic neurons play a key role in transmitting signals from the CNS to the peripheral organs. When an action potential travels down the axon, it reaches the synaptic terminal and triggers the release of neurotransmitters. In the case of sympathetic preganglionic neurons, the primary neurotransmitter released is acetylcholine (ACh), which binds to nicotinic receptors on postganglionic neurons. This neurotransmitter-receptor interaction leads to the activation of postganglionic neurons, which then relay signals to target organs.
