PAMPs interact with the innate immune system through specialized receptors known as Pattern Recognition Receptors (PRRs). These receptors are located on the surface of immune cells such as macrophages, dendritic cells, and neutrophils. When PRRs bind to PAMPs, they initiate a series of intracellular signaling pathways that lead to the production of cytokines and other inflammatory mediators. This interaction is the first line of defense against infections and helps in the activation of the adaptive immune system.
