The identification of morphological alterations typically involves the use of various histological techniques. These include:
Light Microscopy Light microscopy is commonly used to examine stained tissue sections. It allows for the observation of cellular and tissue architecture, as well as the identification of specific morphological changes.
Electron Microscopy Electron microscopy provides a higher resolution than light microscopy and is used to study ultrastructural details of cells and tissues. This technique is particularly useful for identifying subcellular alterations.
Immunohistochemistry Immunohistochemistry involves the use of antibodies to detect specific proteins within cells and tissues. This can help in identifying abnormal protein expression associated with morphological changes.
Histochemical Staining Histochemical staining techniques are used to visualize specific chemical components within cells and tissues. These stains can highlight areas of morphological alteration that are not apparent with standard staining methods.