How Do Macrophages Contribute to Immune Cell Clearance?
Macrophages play a pivotal role in immune cell clearance due to their phagocytic capabilities. They can recognize apoptotic cells via phagocytosis and remove them efficiently. This recognition is often mediated by surface molecules known as pattern recognition receptors (PRRs) that bind to phosphatidylserine exposed on the outer leaflet of the plasma membrane of apoptotic cells.
