Hormones such as antidiuretic hormone (ADH) and aldosterone play crucial roles in water regulation. ADH increases water reabsorption in the kidneys by promoting the insertion of aquaporins in the collecting ducts. Aldosterone enhances sodium reabsorption, which indirectly promotes water retention. Histological changes in endocrine organs, like the pituitary and adrenal glands, can impact hormone levels and water balance.