How Do Histological Features Correlate with Cancer Prognosis?

Histological analysis provides valuable information about the prognosis of cancer:

Grade of Tumor: Tumor grading assesses how much cancer cells resemble normal cells. Higher-grade tumors are usually more aggressive.
Stage of Cancer: Staging determines the extent of cancer spread. Histological analysis of lymph nodes and other tissues helps in staging.
Presence of Necrosis: Areas of necrosis within a tumor often indicate a more aggressive cancer.
Angiogenesis: The formation of new blood vessels within a tumor, visible histologically, can indicate a higher likelihood of metastasis.