Dirty blades can have several detrimental effects on tissue sections:
Tearing: Debris on the blade can cause the tissue to tear during sectioning, resulting in incomplete or unusable sections. Compression: Contaminants can cause the tissue to compress, leading to distorted and uneven sections. Artifacts: Particles and debris can introduce unwanted artifacts, complicating the interpretation of histological slides. Staining Issues: Contaminants can interfere with staining procedures, resulting in uneven or inaccurate staining.
