The three main cytoskeletal components—microfilaments, intermediate filaments, and microtubules—interact with each other and with various cytoskeleton-associated proteins to coordinate cellular functions. For example, microtubules and microfilaments can be linked by cross-linking proteins, which helps in organizing the cytoskeleton and contributing to cellular mechanics. Intermediate filaments can also interact with microtubules and microfilaments to provide additional support and stability to the cell.
