Cytoplasmic changes can be observed under a microscope and may include:
Granular Changes: The appearance of granules due to accumulation of substances like chaperone proteins or aggregates. Vacuolation: Formation of vacuoles which are indicative of cellular injury or autophagy. Swelling: Due to osmotic imbalances or damage to cellular ion pumps. Inclusions: Presence of abnormal substances such as lipid droplets or ribosome aggregates.
