Termination of signal transmission is essential to prevent overstimulation and ensure that cells can respond appropriately to new signals. Termination mechanisms include:
- Degradation of signaling molecules: Enzymes break down signaling molecules. - Desensitization of receptors: Receptors are phosphorylated and internalized, reducing their sensitivity. - Deactivation of second messengers: Enzymes such as phosphodiesterases degrade second messengers like cAMP.
