How do Antigen-Antibody Interactions Work in Immunohistochemistry?
Immunohistochemistry (IHC) relies on antigen-antibody interactions to detect specific proteins in tissues. Antibodies are designed to bind to antigens, which are specific proteins or molecules within the tissue. These antibodies are often tagged with fluorescent or chromogenic labels, allowing for visualization under a microscope. Immunofluorescence and chromogenic detection are common methods used in IHC for this purpose.