How can histological techniques detect PAH-induced damage?
Several histological techniques can be employed to detect PAH-induced damage, including:
- Light microscopy: Used for observing general histopathological changes in tissues. - Immunohistochemistry: Helps in detecting specific proteins that are markers of cellular damage, inflammation, or proliferation. - Electron microscopy: Provides detailed images of cellular ultrastructure, revealing sub-cellular damage. - Histochemical staining: Techniques such as H&E, PAS, and special stains can highlight specific tissue changes and DNA adducts.
