In histological studies, ribosomes can be visualized using various staining techniques. One common method is the use of [hematoxylin and eosin (H&E) staining](). Ribosomes, being rich in RNA, are basophilic and stain darkly with hematoxylin, which binds to acidic components. Electron microscopy provides more detailed images, revealing the intricate structure of ribosomes and their association with the rough ER.
