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nucleic acid content
How are Nucleic Acids Visualized in Tissue Samples?
Several staining techniques are employed to visualize nucleic acids in histological samples:
Hematoxylin and Eosin (H&E) Stain
: Hematoxylin stains the nuclei blue, indicating the presence of DNA and RNA.
Feulgen Reaction
: Specifically stains DNA, turning it magenta.
Methyl Green-Pyronin Stain
: Differentiates DNA (green) and RNA (red).
In Situ Hybridization (ISH)
: Uses labeled probes to detect specific DNA or RNA sequences.
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