How are Lipid Storage Diseases Identified Histologically?
Lipid storage diseases are often identified histologically by the presence of abnormal cells filled with lipid vacuoles. For example: - In Gaucher disease, macrophages (Gaucher cells) appear engorged with a crumpled tissue paper-like appearance. - In Niemann-Pick disease, cells may appear foamy due to the accumulation of sphingomyelin within lysosomes.
