In histology, late endosomes can be studied using various techniques. Immunohistochemistry (IHC) and immunofluorescence (IF) are commonly used to visualize late endosomal markers, such as Rab7 and LAMP1. Electron microscopy provides detailed ultrastructural images, revealing the morphology and internal structure of late endosomes. These techniques help researchers understand the distribution and functional state of late endosomes in different tissues.