ICCs can be identified using specific histological techniques and markers. Immunohistochemistry is a common method, where antibodies against specific proteins such as c-Kit (CD117) are used. c-Kit is a transmembrane receptor tyrosine kinase that is highly expressed in ICCs. Other markers include Ano1 (Anoctamin 1) and vimentin. Histological staining with these markers allows for the precise visualization and study of ICCs in tissue samples.
