How are Endotoxins Detected in Histological Samples?
Detection of endotoxins in histological samples can be achieved through several methods: 1. LAL Test: The Limulus Amebocyte Lysate (LAL) test is a common assay that detects endotoxins based on their ability to cause gelation of the lysate derived from horseshoe crab blood. 2. Histochemical Staining: Specific stains can highlight the presence of endotoxins or the cellular responses they elicit. 3. Immunohistochemistry: Antibodies targeting endotoxin components can be used to visualize their distribution within tissue samples.
