How are Cytotoxic T Lymphocytes Identified Histologically?
In histological studies, CTLs can be identified using immunohistochemistry techniques that tag CD8 molecules with specific antibodies. These tagged molecules can then be visualized using various staining methods, such as fluorescence microscopy or chromogenic substrates. Additionally, CTLs can be found in tissue samples, particularly within the lymphoid organs like the spleen and thymus, as well as in sites of infection or tumor growth.
