Detection of abnormal changes in histology involves several diagnostic techniques:
Histopathology Histopathology is the examination of tissues stained with dyes under a microscope. This technique helps pathologists identify abnormal cellular structures and patterns.
Immunohistochemistry Immunohistochemistry (IHC) uses antibodies to detect specific antigens in tissues. This method is particularly useful for identifying proteins associated with cancer or infectious diseases.
Electron Microscopy Electron microscopy provides detailed images of cell ultrastructure, revealing abnormalities at the molecular level. This technique is essential for diagnosing certain rare diseases.
Molecular Techniques Molecular techniques such as PCR and FISH are used to detect genetic mutations and chromosomal abnormalities. These methods are crucial for diagnosing cancers and genetic disorders.