Why Do Some Pathogens Avoid Phagolysosomal Fusion?
Certain pathogens have evolved mechanisms to avoid phagolysosomal fusion, allowing them to survive and replicate within the host cell. By avoiding this fusion, these pathogens can prevent exposure to the destructive enzymes found in lysosomes, which would otherwise degrade them. This evasion strategy helps pathogens persist in the host, leading to chronic infections.
