The fragility of tissues can be attributed to several factors:
Cellular Composition: Tissues with a high water content or those composed of cells with thin membranes, such as neurons, are more prone to damage. Extracellular Matrix: The composition and density of the extracellular matrix (ECM) also play a crucial role. For instance, tissues with a sparse ECM, like adipose tissue, are more fragile compared to those with a dense ECM, like cartilage. Structural Arrangement: The organization of cells and fibers within the tissue can influence its durability. For example, the stratified layers of epithelial tissues can be more susceptible to mechanical stress.