What Technologies are Used for Genetic Sequencing in Histology?
Several technologies are pivotal in the integration of genetic sequencing and histology:
1. Next-Generation Sequencing (NGS): This high-throughput method allows for the rapid sequencing of large DNA segments, providing detailed genetic information from tissue samples.
2. Single-Cell RNA Sequencing: This technique enables the analysis of gene expression at the single-cell level, offering a granular view of cellular heterogeneity within tissues.
3. Fluorescence In Situ Hybridization (FISH): Often used in conjunction with histological staining, FISH can localize specific DNA sequences within tissue sections, aiding in the visualization of genetic material in its histological context.
