Staining is a critical part of the screening process as it enhances the contrast of tissue structures, making them more visible under the microscope. Common staining techniques include Hematoxylin and Eosin (H&E) staining, which provides a general view of tissue morphology, and immunohistochemistry (IHC), which uses antibodies to detect specific proteins. Other specialized stains, such as Periodic Acid-Schiff (PAS) and Masson's Trichrome, are used for identifying carbohydrates and connective tissue, respectively.