What Role Do Mitochondrial Dynamics Play in Disease Pathology?
Mitochondrial dynamics are critical in the pathology of various diseases. For instance, in cancer, mitochondria often undergo metabolic reprogramming, and an imbalance in fission and fusion can support the high energy demands of rapidly proliferating cells. In neurodegenerative diseases, impaired mitochondrial dynamics can lead to neuronal death and tissue degeneration, which can be studied in histological samples of affected tissues.
