What Pathological Conditions are Associated with Caveolae?
Dysfunction or mutations in caveolin proteins can lead to various diseases:
Caveolinopathies: Genetic mutations in caveolin genes can lead to muscle disorders known as caveolinopathies, such as limb-girdle muscular dystrophy. Cancer: Aberrant expression of caveolins has been implicated in cancer progression and metastasis. Cardiovascular Diseases: Caveolae are involved in the regulation of vascular tone and endothelial function. Alterations can contribute to cardiovascular diseases.
