TRIF, or TIR-domain-containing adapter-inducing interferon-β, is an important signaling molecule in the innate immune response. It plays a crucial role in the activation of immune responses through Toll-like receptors (TLRs), particularly TLR3 and TLR4. These receptors recognize pathogen-associated molecular patterns (PAMPs) and initiate signaling cascades that lead to the production of cytokines and other immune responses.
