What is the Principle Behind Fluorescence In Situ Hybridization (FISH)?
FISH is a technique similar to ISH but uses fluorescently labeled probes to detect specific DNA or RNA sequences in tissue sections. The fluorescence allows for high-resolution visualization of the target sequences under a fluorescence microscope. FISH is commonly used for detecting chromosomal abnormalities, gene amplifications, and translocations in cancer diagnostics and research.
