The bone marrow microenvironment consists of a complex network of cells and extracellular matrix components that support hematopoiesis. This includes:
Stromal Cells: These include fibroblasts, endothelial cells, and adipocytes that provide structural support and secrete growth factors. Macrophages: These cells phagocytose cellular debris and secrete cytokines that influence hematopoiesis. Osteoblasts and Osteoclasts: Cells involved in bone formation and resorption, respectively, which also play a role in regulating the bone marrow niche.
