What is the impact of age-related macular degeneration (AMD) on retinal histology?
In AMD, histological changes include the accumulation of drusen between the RPE and Bruch's membrane, atrophy of the RPE, and degeneration of the photoreceptors. In the advanced stages, there may also be choroidal neovascularization, where new blood vessels grow beneath the retina, leading to leakage and further damage to retinal tissues.
