PXR is of significant clinical interest due to its role in drug metabolism and potential drug-drug interactions. Variations in PXR expression and activity can influence the efficacy and toxicity of medications. Understanding PXR's function can help in predicting individual responses to drugs and in the development of new therapeutic strategies. Moreover, PXR is implicated in conditions such as liver diseases, inflammatory bowel disease, and certain cancers, making it a potential target for therapeutic interventions.
