What is the Clinical Relevance of Pacinian Corpuscles?

Pacinian corpuscles play a crucial role in the sensory system. Dysfunction or damage to these corpuscles can lead to sensory deficits, affecting the ability to perceive pressure and vibration. Conditions such as diabetic neuropathy or other neuropathies can impair the function of Pacinian corpuscles. Additionally, understanding their structure and function is important in reconstructive surgery and for designing prosthetic devices that mimic natural touch sensations.