What is Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCADD)?
Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCADD) is an inherited metabolic disorder that affects the body's ability to convert certain fats to energy, especially during periods of fasting. The deficiency is due to mutations in the ACADM gene, which encodes the enzyme medium-chain acyl-CoA dehydrogenase. This enzyme is crucial for the mitochondrial beta-oxidation of medium-chain fatty acids.
