What is HPV and How Does it Affect Cellular Histology?
Human Papillomavirus (HPV) is a group of viruses that can cause infections in the epithelial cells of the skin and mucous membranes. Histologically, HPV infection can lead to cellular changes, including koilocytosis, where cells exhibit perinuclear halos and nuclear enlargement. These changes are particularly evident in the cervix, where HPV infection can progress to cervical intraepithelial neoplasia (CIN) and, ultimately, cervical cancer if untreated.
