Erythroblastosis Fetalis, also known as Hemolytic Disease of the Newborn (HDN), is a potentially severe condition that occurs when there is an incompatibility between the blood types of the mother and the fetus. This leads to the destruction of fetal red blood cells by maternal antibodies. In most cases, this condition is associated with Rh incompatibility, where an Rh-negative mother carries an Rh-positive fetus.