duration of fixation

What Happens if Fixation is Too Short or Too Long?

Inadequate fixation can result in:

Loss of cellular detail
Distortion of tissue morphology
Autolysis and bacterial contamination

On the other hand, over-fixation can lead to:

Excessive hardening of tissues
Difficulty in sectioning
Masking of antigenic sites, affecting immunohistochemistry results

Frequently asked queries:

What is Fixation in Histology?

Why is the Duration of Fixation Important?

What Factors Influence the Duration of Fixation?

What is the Recommended Duration for Common Fixatives?

What Happens if Fixation is Too Short or Too Long?

How Can One Determine the Optimal Fixation Duration?

Are There Any Modern Techniques to Enhance Fixation?

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