Several pathological conditions are associated with the presence of microcytes:
1. Iron Deficiency Anemia: The most common cause of microcytes is iron deficiency anemia. In this condition, the body lacks sufficient iron to produce hemoglobin, resulting in smaller RBCs. 2. Thalassemia: This genetic disorder affects hemoglobin production, leading to the formation of small, abnormally shaped RBCs. 3. Chronic Disease Anemia: Chronic inflammatory diseases can interfere with iron metabolism and RBC production, leading to microcytosis. 4. Lead Poisoning: Exposure to lead can disrupt hemoglobin synthesis, resulting in the formation of microcytes.
