What Challenges Are Associated with Antibody Complexes in Histology?
One of the main challenges in using antibody complexes in histology is the specificity and sensitivity of the antibodies. Non-specific binding can lead to background staining, complicating the interpretation of results. Additionally, the antigen retrieval process, which involves exposing tissue samples to conditions that unmask antigens, can sometimes damage the tissue or alter antigenicity, affecting the accuracy of the results.
