Metamorphosis involves dramatic cellular changes, particularly in holometabolous insects. Larval tissues undergo programmed cell death, or [apoptosis](#), while adult structures differentiate from clusters of undifferentiated cells called [imaginal discs](#). These discs proliferate and differentiate to form adult tissues such as wings, legs, and eyes. Hormonal regulation, primarily by ecdysteroids and juvenile hormones, plays a crucial role in coordinating these cellular events.
