Abnormal aPTT results can indicate a range of conditions. A prolonged aPTT may suggest deficiencies in clotting factors, the presence of inhibitors, or the effects of certain medications like heparin. In histological analysis, these abnormalities can manifest as increased bleeding, abnormal clot formation, or tissue necrosis. Conditions such as lupus anticoagulant or antiphospholipid syndrome often require both aPTT testing and histological examination for accurate diagnosis.
