What are the Pathological Implications of Ceruloplasmin Dysregulation?
Dysregulation of ceruloplasmin can lead to several pathological conditions: - Wilson's Disease: Characterized by low ceruloplasmin levels and copper accumulation in tissues. - Aceruloplasminemia: A rare genetic disorder resulting in iron overload in various organs due to the absence of functional ceruloplasmin. - Inflammatory Diseases: Elevated ceruloplasmin levels are often seen in chronic inflammatory diseases and can serve as a marker for acute-phase reactions.
