What are the Pathological Conditions Associated with Pappenheimer Bodies?
Several pathological conditions are associated with the presence of Pappenheimer bodies. These include: - Sideroblastic anemia: Characterized by ineffective erythropoiesis and ringed sideroblasts in the bone marrow. - Myelodysplastic syndromes: A group of disorders caused by poorly formed or dysfunctional blood cells. - Hemolytic anemias: Such as thalassemia and hereditary spherocytosis, where there is increased RBC destruction. - Post-splenectomy: Patients who have had their spleen removed may also show Pappenheimer bodies due to the spleen's role in filtering abnormal RBCs.
