Collagen: The most abundant protein in the ECM, providing tensile strength and structural support. Elastin: Provides elasticity, allowing tissues to resume their shape after stretching or contracting. Proteoglycans: Composed of a core protein and glycosaminoglycan (GAG) chains, they provide hydration and resistance to compressive forces. Fibronectin and Laminin: Glycoproteins that facilitate cell adhesion and migration.